![]() Thinning of the outer layer of compact bone greatly reduces its strength and increases the likelihood of fracture. Thus in osteoporosis, the amount of both compact and spongy bone is reduced. After menopause or after middle age when the level of hormones go down ,the new bone forming cells also cease to function normally. The osteoblasts then move into these spaces and produce new bone. The osteoclasts function to dissolve older bone and leave tiny unfilled spaces behind. Two types of cell regulate the growth of bone: osteoclasts and osteoblasts. Normally, bones are composed of a shell of compact or solid bone surrounding connecting plates and rods of bone (spongy bone) within which lie the bone marrow. It is a slow, progressive disease characterized by a gradual loss of calcium from bones until they become very porous and weak. Osteoporosis literally means porous bones. Allantoin is known to stimulate osteoblasts, the bone building cells. Allantoin is known to stimulate cell proliferation and so augments wound-healing both inside and out. The impressive wound-healing properties of Symphytum are due to the presence of allantoin. Symphytum is a homoeopathic medicine made from root and leaves of the plant called Comfrey or Symphytum Officinale and is usually used homeopathically in a highly diluted form. Its extreme effectiveness in treating osteoporosis and healing fractures is what puts it into this category. ![]() One such medicine from the homoeopathic system of medicine is Symphytum Officinale. Slowly a lot many medicines from different disciplines are being accepted into the mainstream medicine because of their high efficacy in treating a particular illness. It is being replaced by a more holistic term ‘integrated medicine’ where the best of all the system integrate to serve the humanity at its best. As a new finding, applicability in certain forms of back pain can be concluded.As the gap between the various medical systems narrows down, the term ‘alternative medicine’ is slowly dying a well deserved death. Study results confirm the known anti-inflammatory and analgesic effects of topical (Symphytum cream. Tolerability of the highly concentrated study product was good to excellent in all patients. Global efficacy was significantly better (P=1 x 10 -8 ) and onset of effects was faster (P=4 x 10 -7 ) with the high-concentration product. ![]() A number needed to treat of 3.2 was calculated from the study results. With high concentrations of the treatment product, amelioration of pain on active motion (P<5 x 10 -9 ), pain at rest (P<.001), and pain on palpation (P=5 x 10 -5 ) was significantly more pronounced than that attained with the reference product and was clinically highly relevant. Secondary efficacy parameters included pain at rest, pain on palpation, and functional impairment. The primary efficacy parameter in this double-blind, reference- controlled, randomized, multicenter study of 215 patients with pain in the lower and upper back was pain in motion, assessed with the aid of a visual analogue scale. The effectiveness and tolerability of the topical Symphytum product Traumaplant (Harras Pharma Curarina, München, Germany) (10% active ingredient of a 2.5:1 aqueous-ethanolic pressed concentrate of freshly harvested, cultivated comfrey herb, corresponding to 25 g of fresh herb per 100 g of cream) in the treatment of patients with myalgia (n=104) were tested against a 1% reference product (corresponding to 2.5 g of fresh comfrey herb in 100 g of cream n=111). ![]()
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